FIG. 1.

Photographs of inclusions in infected HFF cells and the effect of antiviral drugs on their formation. All images were obtained with a 100× objective and are shown merged with images of DAPI staining. Phase-contrast images of HFF cells infected with RCΔ97.08 (A) or AD169 with the addition of 15 μM MBV (B) are shown at 72 hpi. The formation of aggregates at 96 hpi was visualized with monoclonal antibody to pp65 (28-19) in AD169-infected cells without the addition of drug (C), with 15 μM MBV (D), with 15 μM BDCRB (E), or with cidofovir (F). Localization of aggregates in cells infected with RCΔ97.08 was visualized with an anti-pp65 monoclonal antibody at 48 hpi (G) and 72 hpi (H).