Table 1.

In silico screening using AUTODOCK v3.0.5

Compounds	MtuLigANAD	EfaLigA	T4Lig	HuLigI
NAD	−14.7	−14.9	—	—
AMP	−10.7	−11.9	−9.3	−10.8
Chloroquine	−10.7	−10.8	−9.3	−10.6
Doxorubicin	−18.6	−19.7	−13.7	−17.0
Pyridochromanone 3	−16.7	−17.7	−13.5	−17.7
1	−15.8	−16.9	−12.4	−12.6
2	−11.2	−12.2	−11.7	−11.0
3	−13.8	−11.8	−10.7	−12.0
4	−14.3	−15.2	−13.0	−14.9
5	−11.2	−12.1	−13.3	−14.4

The docking energies are in kcal/mol. MtuLigA_NAD, EfaLigA, T4Lig and HuLigI refer to the respective ligases from M.tuberculosis, E.faecalis, T4 bacteriophage and human sources mentioned in the text.