Table 2.
Associations between CMR indices and atrial fibrillation
| CMR (per 1SD) |
Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P | |
| LV-EDV | 1.326 (1.259, 1.398) | < 0.001 | 1.307 (1.235, 1.384) | < 0.001 | 1.296 (1.225, 1.371) | < 0.001 |
| LV-ESV | 1.289 (1.249, 1.329) | < 0.001 | 1.299 (1.255, 1.345) | < 0.001 | 1.279 (1.235, 1.325) | < 0.001 |
| LV-SV | 1.060 (0.999, 1.125) | 0.054 | 1.035 (0.973, 1.100) | 0.274 | 1.042 (0.980, 1.108) | 0.187 |
| LV-EF | 0.725 (0.692,0.760) | < 0.001 | 0.730 (0.695, 0.766) | < 0.001 | 0.745 (0.709, 0.782) | < 0.001 |
| RV-EDV | 1.169 (1.094, 1.250) | < 0.001 | 1.136 (1.061, 1.217) | < 0.001 | 1.151 (1.075, 1.233) | < 0.001 |
| RV-ESV | 1.369 (1.288, 1.454) | < 0.001 | 1.339 (1.257, 1.426) | < 0.001 | 1.345 (1.263, 1.433) | < 0.001 |
| RV-SV | 0.938 (0.881, 0.997) | 0.041 | 0.919 (0.863, 0.979) | 0.009 | 0.932 (0.876, 0.993) | 0.030 |
| RV-EF | 0.732 (0.698, 0.768) | < 0.001 | 0.741 (0.706, 0.777) | < 0.001 | 0.750 (0.715, 0.786) | < 0.001 |
| LAVmax | 1.755 (1.697, 1.816) | < 0.001 | 1.725 (1.665, 1.788) | < 0.001 | 1.714 (1.653, 1.778) | < 0.001 |
| LAVmin | 1.584 (1.554, 1.615) | < 0.001 | 1.554 (1.523, 1.585) | < 0.001 | 1.551 (1.520, 1.582) | < 0.001 |
| LA-SV | 0.990 (0.937, 1.045) | 0.708 | 0.961 (0.908, 1.016) | 0.163 | 0.958 (0.906, 1.014) | 0.139 |
| LA-EF | 0.437 (0.421, 0.454) | < 0.001 | 0.454 (0.437, 0.473) | < 0.001 | 0.458 (0.440, 0.476) | < 0.001 |
| RAVmax | 1.517 (1.450, 1.586) | < 0.001 | 1.492 (1.425, 1.562) | < 0.001 | 1.508 (1.440, 1.578) | < 0.001 |
| RAVmin | 1.646 (1.585, 1.708) | < 0.001 | 1.614 (1.553, 1.677) | < 0.001 | 1.615 (1.555, 1.678) | < 0.001 |
| RA-SV | 1.037 (0.983, 1.094) | 0.180 | 1.028 (0.974, 1.085) | 0.321 | 1.042 (0.987, 1.100) | 0.134 |
| RA-EF | 0.605 (0.569, 0.643) | < 0.001 | 0.624 (0.587, 0.663) | < 0.001 | 0.629 (0.592, 0.669) | < 0.001 |
Model 1 was adjusted by age, sex, race, education, and income
Model 2 was adjusted by Model 1 + physical activity, smoke, alcohol, DASH, and PRS
Model 3 was adjusted by Model 2 + history of diabetes mellitus, hypertension, other CVD, and cancer
DASH Dietary approaches to stop hypertension, PRS Polygenic risk score, CVD Cardiovascular diseases, CMR Cardiac magnetic resonance imaging, LV-EDV Left ventricular end diastolic volume, LV-ESV Left ventricular end systolic volume, LV-SV Left ventricular stroke volume, LV-EF Left ventricular ejection fraction, RV-EDV Right ventricular end diastolic volume, RV-ESV Right ventricular end systolic volume, RV-SV Right ventricular stroke volume, RV-EF Right ventricular ejection fraction, LAVmax Left atrial maximum volume, LAVmin Left atrial minimum volume, LA-SV Left atrial stroke volume, LA-EF Left atrial ejection fraction, RAVmax Right atrial maximum volume, RAVmin Right atrial minimum volume, RA-SV Right atrial stroke volume, RA-EF Right atrial ejection fraction