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. 2005 Nov 22;392(Pt 2):313–324. doi: 10.1042/BJ20050636

Figure 1. G0S2 is a PPARα-regulated gene in mouse.

Figure 1

(A) Hepatic expression of G0S2 after 0, 6, 12 or 24 h of fasting in wild-type (■) and PPARα-null mice (□). (B) Hepatic G0S2 expression in wild-type (+/+) and PPARα-null (−/−) mice 6 h after oral gavage of 4 mg of Wy14643. (C) Hepatic G0S2 expression in wild-type (+/+) and PPARα-null (−/−) mice after 5 days of feeding with Wy14643 (0.1%). (D) G0S2 expression in primary hepatocytes of wild-type (+/+) and PPARα-null (−/−) mice incubated for 24 h in the presence or absence of Wy14643 (25 μM). (E) G0S2 expression in primary rat hepatocytes incubated for 24 h in the presence or absence of Wy14643 (25 μM). G0S2 expression was determined by Q-PCR. Results are means±S.E.M. Differences were evaluated by student's t test (*P<0.05, **P<0.01, ***P<0.001).