Figure 2. Respiration rates of skeletal-muscle mitochondria from wild-type and ANT1 knock-out (ANT KO) mice.

(A) Respiratory control ratios with 4 mM succinate as substrate (state-3 rate with 700 μM ADP added/state-4 rate). (B) Respiration rates in state 3 (solid bars) and state 4 (part-shaded bars). Replicate measurements were performed on each preparation and averaged. Values are means±S.E.M. from three independent preparations. *P<0.05 compared with wild-type in the same condition.