Table 2. Glycolytic enzyme activities in the haemolysates of members of the Hungarian TPI-deficient family.
Data are the means for three to five measurements. At least five different sets of experiments were carried out and the means±S.D. are shown. LDH, lactate dehydrogenase.
| Enzyme activity (units/g of haemoglobin) | |||||||
|---|---|---|---|---|---|---|---|
| HK | PFK | Aldolase | TPI | GAPDH | LDH | Pyruvate kinase | |
| Control | 0.57–0.67 | 14.9–19.7 | 3.6–5.6 | 1400–2100 | 100–160 | 130–190 | 4.7–6.7 |
| Mother | 0.70±0.08 | 18.6±2.5 | 5.0±0.6 | 737±60 | 150±18 | 190±10 | 5.6±0.7 |
| Father | 0.70±0.07 | 20.1±3.0 | 5.0±0.6 | 1180±165 | 145±20 | 164±20 | 5.0±0.5 |
| Brother | 1.30±0.18 | 33.4±5.0 | 6.7±1.5 | 44.0±14.5 | 239±22 | 222±16 | 9.4±0.8 |
| Patient | 1.47±0.22 | 34.3±5.0 | 6.7±1.3 | 36.5±12.5 | 214±21 | 159±10 | 9.9±1.1 |