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. 2026 Apr 29;15(9):804. doi: 10.3390/cells15090804
GLP-1 Glucagon-Like Peptide 1
GLP-1R Glucagon-Like Peptide 1 Receptor
GLP-1RAs Glucagon-Like Peptide 1 Receptor Agonists
GPCR G-protein-coupled receptors
GIP Glucose-dependent insulinotropic polypeptide
PD Parkinson’s Disease
AD Alzheimer’s Disease
T2DM Type 2 diabetes mellitus
BBB Blood–brain barrier
CNS Central Nervous System
PNS Peripheral nervous system
cAMP Cyclic Adenosine Monophosphate
CREB cAMP response element-binding protein
PKA Protein Kinase A
PI3K Phosphoinositide 3-Kinase
AKT Protein Kinase B
ERK Extracellular Signal-Regulated Kinase
MAPK Mitogen-activated protein kinases
EPAC Exchange protein activated by cAMP
mTOR Mammalian target of rapamycin
GSK-3β Glycogen synthase kinase-3β
FOXO1 Forkhead box O1
DNA Deoxyribonucleic acid
RNA Ribonucleic acid
APE1 Apurinic/Apyrimidinic endonuclease 1
BER Base excision repair
Ex4 Exendin-4
MPZ Myelin protein zero
PMP22 Peripheral myelin protein 22
IFRS1 Immortalised Fischer rat Schwann cells
MS Multiple sclerosis
IL-1β Interleukin-1 beta
IL-6 Interleukin-6
IL-17 Interleukin-17
TNF-α Tumour necrosis factor-alpha
Th1 T helper type 1
Th17 T helper type 17
ROS Reactive oxygen species
HDAC6 Histone Deacetylase 6
LC3 Microtubule-associated protein 1A/1B-light chain 3
SCI Spinal cord injury
PtdIns3P Phosphatidylinositol-3-phosphate
AGEs Advanced glycation end-products
NTS Nucleus tractus solitarius
ARC Arcuate nucleus
PVN Paraventricular nucleus
VMH Ventromedial hypothalamic nucleus
DMV Dorsal motor nucleus of the vagus
POMC Proopiomelanocortin
CSF Cerebrospinal fluid
DPP-4 Dipeptidyl peptidase-4
DPP-4i Dipeptidyl peptidase-4 inhibitors
PYY Peptide YY
LPS Lipopolysaccharide
HFD High-fat diet
MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
SCFAs Short chain fatty acids
GPR41/43 G protein-coupled receptor 41/43
DKD Diabetic kidney disease
NAFLD Non-alcoholic fatty liver disease
DCA Deoxycholic acid
PBMC Peripheral blood mononuclear cell
IGF-1 Insulin-like growth factor-1
STAT3 Signal transducer and activator of transcription
APP Amyloid Precursor Protein
PS1 Presenilin 1
5xFAD Five familial Alzheimer’s Disease mutation
STZ Streptozotocin
NLRP2 NLR family pyrin domain containing 2
GluR1 Glutamate receptor 1
PSD-95 Postsynaptic density protein-95
BDNF Brain-derived neurotrophic factor
ADAM10 A disintegrin and metalloproteinase domain-containing protein 10
RCTs Randomised controlled trials
PET Positron Emission Tomography