Table 1. Comparison of reported cases of Cutibacterium acnes pleuropulmonary infection.
COPD: chronic obstructive pulmonary disease; bid: bis in die (twice a day); tid: ter in die (three times a day)
| Variable | Current case | Adlakha and Muppala [10] | Veitch et al. [17] | Cobo et al. [4] |
| Age (years) | 34 | 57 | 29 | 66 |
| Sex | Male | Male | Male | Male |
| Co morbidities | None | COPD with bullous emphysema | Restrictive cardiomyopathy with cardiac transplant; | Rheumatoid arthritis and COPD |
| Smoking history | Yes | Yes | Non-smoker | Yes |
| Immunocompetence | Competent | Competent | Compromised: mycophenolate mofetil; cyclosporine | Competent |
| Localization | Lung | Lung | Lung | Pleural |
| Clinical presentation | Persistent respiratory infection, hemoptysis, fever, weight loss | Recurrent respiratory infections without fevers or weight loss | Fevers, cough, and left chest pain | Asthenia, dyspnea, hemoptysis, and chest pain |
| Diagnosis | C. acnes pulmonary abscess | C. acnes pulmonary abscess | C. acnes pulmonary abscess | C. acnes pleural empyema |
| Treatment | Ceftriaxone 2g, six weeks | Doxycycline 100 mg bid, 21 days | Co‑amoxiclav 625 mg tid, six weeks | Moxifloxacin 400mg |
| Follow‑up/ prognosis | Favorable clinical, biological, and radiological evolution. | Radiological resolution; patient remained well. | 7 months after the initial presentation, the patient remained well | Patient is being treated for cancer |