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. 2026 Apr 12;18(4):e106894. doi: 10.7759/cureus.106894

Table 1. Comparison of reported cases of Cutibacterium acnes pleuropulmonary infection.

COPD: chronic obstructive pulmonary disease; bid: bis in die (twice a day); tid: ter in die (three times a day)

Variable Current case Adlakha and Muppala [10] Veitch et al. [17] Cobo et al. [4]
Age (years) 34 57 29 66
Sex Male Male Male Male
Co morbidities None COPD with bullous emphysema Restrictive cardiomyopathy with cardiac transplant; Rheumatoid arthritis and COPD
Smoking history Yes Yes Non-smoker Yes
Immunocompetence Competent Competent Compromised: mycophenolate mofetil; cyclosporine Competent
Localization Lung Lung Lung Pleural
Clinical presentation Persistent respiratory infection, hemoptysis, fever, weight loss Recurrent respiratory infections without fevers or weight loss Fevers, cough, and left chest pain Asthenia, dyspnea, hemoptysis, and chest pain
Diagnosis C. acnes pulmonary abscess C. acnes pulmonary abscess C. acnes pulmonary abscess C. acnes pleural empyema
Treatment Ceftriaxone 2g, six weeks Doxycycline 100 mg bid, 21 days Co‑amoxiclav 625 mg tid, six weeks Moxifloxacin 400mg
Follow‑up/ prognosis Favorable clinical, biological, and radiological evolution.    Radiological resolution; patient remained well. 7 months after the initial presentation, the patient remained well Patient is being treated for cancer