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. 2005 Dec;25(24):10768–10781. doi: 10.1128/MCB.25.24.10768-10781.2005

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FIG. 9. — Wild-type mice with E14.5 Prep1^i/i FL cells transplanted recapitulate the phenotype of Prep1^i/i mice. (A) Thymocyte analysis of wild-type mice transplanted with wild-type or Prep1^i/i fetal liver cells. The total number of donor-derived thymocytes (gated on CD45.2-positive cells), the number of CD45.2⁺ DN, DP, SP CD4⁺ (CD4). and SP CD8⁺ (CD8), αβTCR (αβ), and γδTCR (γδ) thymic cells are shown. Notice the different scale of the ordinate in the right graph. (B) Analysis of lymphocytes from the spleens and lymph nodes of mice transplanted with wild-type or Prep1^i/i fetal liver cells. The absolute number of CD4⁺ and CD8⁺ donor-derived (gated on CD45.2-positive) T cells is shown. Values that were significantly different or not significantly different are indicated as follows: *, P < 0.05; **, P < 0.01; ***, P < 0.001; NS, not statistically significant.