TABLE 5.

Altered regulation to uranium in wild type and ΔCC1293 and ΔCC1294 mutants^a

Gene	Regulation of:
	Wild type			ΔCC1293			ΔCC1294
	−U	+U	P value	−U	+U	P value	−U	+U	P value
CC3291	995	3,296	0.02	2,500	5,000	0.06	2,300	2,585	0.76
CC0139	460	1,390	0.02	989	813	0.45	1,013	1,458	0.03
CC3446	1,190	304	0.01	852	561	0.3	803	1,107	0.1
CC2334	1,481	229	0.004	1,097	729	0.3	977	614	0.05
CC1293	482	6,303	0.006	40	10	0.43	150	864	0.008
CC1294	946	8,220	0.006	600	6,500	0.004	91	20	0.38

^aNumbers in the −U or +U columns are expression levels (average difference scores); each was an average of three independent experiments. Numbers in the P value columns represent results from a t test. Genes were differentially regulated under uranium stress in a wild-type (CB15N) background, but the regulation was lost or altered when either CC1293 or CC1294 was deleted, except CC1293 and CC1294 were included to demonstrate the loss of the respective genes in the mutants. Evidently the regulation of the CC1293-CC1294 operon is still maintained.