TABLE 3.
Output of the kNN interpretative algorithm for the samples collected at a rheumatology clinic compared to rheumatologist-assigned diagnosesa
| Physician's diagnosis | Total no. of samples | No. of patients with positive antibody results | No. of samples with the following kNN outputb:
|
Total no. of output results | |||||
|---|---|---|---|---|---|---|---|---|---|
| SLE | MCTD | Scleroderma | SS | PMYO | NA | ||||
| No CTD | 38 | 5 | 0 | 0 | 0 | 0 | 0 | 5 | 5 |
| Nontargeted CTD | 90 | 24 | 8 | 0 | 1 | 1 | 1 | 14 | 25 |
| SLE | 32 | 30 | 25 | 3 | 3 | 3 | 0 | 3 | 37 |
| SLE and MCTD | 2 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 3 |
| MCTD | 4 | 4 | 4 | 2 | 0 | 0 | 0 | 0 | 6 |
| Scleroderma | 4 | 3 | 0 | 0 | 3 | 0 | 0 | 0 | 3 |
| Sjögren's syndrome | 2 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 2 |
| Polymyositis | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
| Total | 173 | 70 | 40 | 6 | 7 | 5 | 2 | 22 | 82 |
a
Note that the total number of output results from the kNN interpretative algorithm exceeds the number of patients with positive antibody results, because some samples were associated with more than one disease.
b
SS, Sjögren's syndrome; PMYO, polymyositis; NA, no association. The values in bold type show results where the kNN output and clinical assessment are in concordance.