TABLE 2.
Clinical features, HBV genotypes, HBV DNA levels, and liver inflammation in relation to HBeAg and clinical status
HBeAg and clinical status | No. of patients | Age (yr) | Sex (no. of males:no. of females) | No. infected with genotype B:no. infected with genotype C | ALT level (U/liter) | HBV DNA concn (log pg/ml) | HAI inflammation score | HAI fibrosis score |
---|---|---|---|---|---|---|---|---|
HBeAg positive | ||||||||
Asymptomatic carriers | 28 | 31.6 ± 8.9 | 13:15 | 20:8 | 25.3 ± 13.2 | |||
Chronic hepatitis patients | 59 | 34 ± 10.0a | 45:14 | 37:19 | 201.9 ± 169.5 | 2.8 ± 1.0c | 6.4 ± 3.7 | 0.8 ± 1.1 |
Liver cirrhosis patients | 16 | 44.4 ± 12 | 15:1 | 4:12 | 87.5 ± 58.6 | 2.0 ± 1.2d | 6.4 ± 4.5 | 4 |
Subtotal | 103 | 35 ± 10.8b | 73:30 | 61:39 | 136.1 ± 152.1 | 2.6 ± 1.1e | 6.4 ± 3.8 | 1.5 ± 1.6f |
HBeAg negative | ||||||||
Asymptomatic carriers | 38 | 31.7 ± 11.3 | 22:16 | 32:6 | 22.8 ± 9.9 | |||
Chronic hepatitis patients | 36 | 40.5 ± 12.1a | 31:5 | 28:8 | 161.5 ± 212.9 | 1.7 ± 1.0c | 5.6 ± 3.4 | 0.9 ± 1.2 |
Liver cirrhosis patients | 23 | 45.8 ± 12 | 18:5 | 10:13 | 147.4 ± 154.6 | 1.3 ± 1.0d | 6.4 ± 2.5 | 4 |
Subtotal | 97 | 38.4 ± 12.9b | 71:26 | 70:27 | 103.8 ± 162.3 | 1.5 ± 1.0e | 5.9 ± 3.1 | 2.1 ± 1.8f |
P = 0.0056.
P < 0.001.
P < 0.001.
P = 0.057.
P < 0.001.
P = 0.044.