TABLE 2.
Toxoplasma-specific IgG reactivity of 104 serum samples from 104 infants of mothers with primary T. gondii infection in pregnancy
| Groupa | No. of samples | Mean IgG levelb (IU/ml) | No. (%) [P]c of samples reactive in IgG Rec-ELISA against:
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| MIC2a | MIC2b | MIC3 | MIC4 | M2AP | AMA1 | SAG1 | |||
| Infected | 35 | 338 | 34 (97) | 29 (83) | 33 (94) | 17 (49) | 31 (89) | 20 (57) | 24d (75) |
| Uninfected | 69 | 61 | 34 (49) [<0.0001] | 22 (32) [<0.0001] | 20 (29) [<0.0001] | 2 (3) [<0.0001] | 30 (43) [<0.0001] | 10 (15) [<0.0001] | 23 (33) [<0.0001] |
| Controls | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |
a
Serum samples collected from: A, newborns with congenital toxoplasmosis; B, uninfected infants; C, Toxoplasma-seronegative controls.
b
Toxoplasma-specific IgG levels, expressed as International Units (IU).
c
Chi-square test comparing uninfected and infected newborns.
d
Only 32 samples tested against SAG1.