TABLE 5.
Diagnostic performance of the IgM-capture assays based on recombinant antigensa
| IgM Rec-ELISA antigen(s) | Sensitivity (%) | Specificity (%) | Agreement (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|
| MIC2a | 60 | 100 | 86.5 | 100 | 83.1 |
| MIC2b | 51.4 | 98.6 | 82.7 | 94.7 | 80 |
| MIC3 | 31.4 | 100 | 76.9 | 100 | 74.2 |
| M2AP | 48.6 | 98.6 | 81.7 | 94.4 | 79.1 |
| SAG1 | 65.7 | 95.8 | 85.6 | 88.5 | 84.6 |
| MIC2a + SAG1 | 85.7 | 95.8 | 92.3 | 90.9 | 93 |
| MIC2a + MIC3 | 65.7 | 100 | 88.5 | 100 | 85.2 |
| MIC2a + MIC2b + SAG1 | 94.3 | 94.5 | 94.2 | 89.2 | 97 |
| MIC2a + MIC3 + SAG1 | 88.6 | 95.8 | 93.3 | 91.2 | 94.3 |
| MIC2a + MIC2b + MIC3 | 71.4 | 98.6 | 89.4 | 96.2 | 87.2 |
a
PPV, positive predictive value; NPV, negative predictive value.