TABLE 2.
Comparison of epidemiological and clinical data of 5 patients with ISF and 19 patients with classical MSF
| Feature or sign | Value for:
|
P valueb | |
|---|---|---|---|
| ISF patients (n = 5) | MSF patients (n = 19)a | ||
| No. of males/females | 3/2 | 14/5 | NS‡ |
| Mean age (range) (yr) | 49 (29-60) | 54 (26-74) | NS§ |
| Mean period between onset and hospitalization (days) | 6.8 | NA | |
| Mean stay at the hospital (days) | 14.6 | NA | |
| No. of patients with: | |||
| Maculopapular rash | 5 | 19 | NS‡ |
| Eschar | 2 | 12 | NS‡ |
| DICc | 3 | 1 | <0.05‡ |
| Coma | 3 | 1 | <0.05‡ |
| Exitus | 1 | 1 | NS‡ |
a
NA, not available.
b
NS, not significant. ‡, P value calculated by the χ2 test. §, statistical significance calculated by analysis of variance through the F test.
c
Diagnosed based on the following laboratory signs: thrombocytopenia (<100,000/mm3), prolonged prothrombin time (>15 s) and activated partial thromboplastin time (>40 s), and presence of fibrin degradation products (>10 μg/ml) and/or d-dimer (>0.5 μg/ml).