TABLE 3.

Serological data of five patients with R. conorii subsp. israelensis infection

Patient no.	Datea of:		Serum sampling		Titer by the following serological testc:
	Disease onset	Start of antimicrobial treatmentb	No. of sera	Collection datea	ELISA		IIF
					IgM	IgG	IgM	IgG
1	09/03/1991	09/10	1	09/12	0	1/400	0	0
			2	09/16	0	1/800	0	0
2	08/29/1995	09/07	1	09/07	0	0	0	0
			2	09/26	1/3,200	1/800	1/320	1/320
3	06/16/2000	06/21	1	06/21	0	0	0	0
			2	06/27	1/200	1/200	1/80	1/160
			3	07/04	1/800	1/1,600	1/320	1/640
4	07/31/2000		1	08/05	1/50	0	1/40	0
5	07/02/2001	07/16	1	07/11	1/100	0	1/40	0
			2	07/16	1/400	1/100	1/640	1/640
			3	07/19	1/800	1/200	1/1,280	1/640
			4	08/02	1/1,600	1/200	1/1,280	1/1,280
			5	10/24	1/1,600	1/800	1/1,280	1/1,280
			6	02/11/2002	1/800	1/3,200	1/1,280	1/1,280

^aDates are given as mo/day/yr or mo/day.

^bDoxycycline therapy.

^cBoth an ELISA and an IIF assay were performed with freshly prepared antigens obtained from a clinical isolate of R. conorii subsp. conorii (strain MAVI) as described previously (23).