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Tms and deviations in Tms of probes RpoSP1 and RpoSP2
| Codon (mutation) | RpoSP1 Tm (°C) | ΔTma (°C) of RpoSP1 | RpoSP2 Tm (°C) | ΔTm (°C) of RpoSP2 |
|---|---|---|---|---|
| M. tuberculosis H37Ra | 77.50 | 66.29 | ||
| 513 (Gly→Leu) (n = 2)b | 77.70 | 0 | 63.06 | 3.23 |
| 516 (Asp→Val) (n = 5) | 77.50 | 0 | 62.54 | 3.75 |
| 516 (Asp→Tyr) (n = 4) | 77.50 | 0 | 60.53 | 5.76 |
| 526 (His→Glu) (n = 20) | 72.75 | 4.75 | 66.29 | 0 |
| 531 (Ser→Leu) (n = 58) | 71.47 | 6.03 | 66.29 | 0 |
ΔTm, change in Tm.
n, number of isolates predicted by probe Tms.
