TABLE 2.
Serotypes, resistance profiles, MLSTs, and PFGE types of 26 antibiotic-resistant S. pneumoniae isolates in South Africa from 1977 to 1978
| Isolate | Serotype | Resistance profilea | Sequence type at allele:
|
MLST | PFGE type | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| aroE | gdh | gki | recP | spi | xpt | ddl | |||||
| 641 | 19A | PCS | 1 | 8 | 9 | 5 | 11 | 1 | 12 | 41 | C3 |
| 636 | 19A | PCS | 1 | 8 | 9 | 5 | 11 | 1 | 12 | 41 | C2 |
| 632 | 19A | PMLCTS | 1 | 8 | 9 | 5 | 11 | 1 | 12 | 41 | B |
| 644 | 19A | PMLCTS | 1 | 8 | 9 | 5 | 11 | 1 | 12 | 41 | C2 |
| 635 | 19A | PMLCTS | 1 | 8 | 9 | 5 | 11 | 1 | 12 | 41 | C1 |
| 639 | 19A | PMLCTS | 1 | 8 | 9 | 5 | 11 | 1 | 12 | 41 | D |
| 623 | 19A | PMLCTS | 1 | 8 | 9 | 5 | 11 | 1 | 165 | 1605 | E |
| 634 | 19A | PMLCTS | 1 | 8 | 9 | 5 | 11 | 1 | 165 | 1605 | C |
| 643 | 19A | PCS | 1 | 8 | 9 | 5 | 11 | 1 | 165 | 1605 | C3 |
| 638 | 19A | PCS | 2 | 8 | 9 | 5 | 11 | 1 | 13 | 1656 | C4 |
| 620 | 6A | PMLTS | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | A1 |
| 622 | 6A | PTS | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | A1 |
| 624 | 6A | PMLTS | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | A1 |
| 626 | 6A | PMLTS | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | A1 |
| 630 | 6A | P | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | F |
| 631 | 6A | PTELS | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | A1 |
| 633 | 6A | PS | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | F1 |
| 642 | 6A | PS | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | F |
| 645 | 6A | PMLTS | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | A1 |
| 628 | 6A | PMLTS | 6 | 62 | 5 | 30 | 88 | 8 | 6 | 1094 | A |
| 621 | 6A | PTS | 6 | 62 | 5 | 30 | 88 | 149 | 6 | 1607 | A2 |
| 629 | 14 | p | 7 | 5 | 1 | 8 | 14 | 11 | 14 | 124 | G |
| 637 | 19A | p | 7 | 13 | 8 | 6 | 25 | 6 | 8 | 172 | H |
| 625 | 19A | p | 10 | 11 | 4 | 1 | 6 | 149 | 5 | 1608 | I |
| 640 | 19A | p | 10 | 11 | 4 | 1 | 6 | 149 | 5 | 1608 | K |
| 627 | 19A | p | 10 | 99 | 4 | 1 | 6 | 149 | 5 | 1610 | J |
Abbreviations: p, penicillin G intermediate; P, penicillin G resistant; M, macrolide resistant; L, lincosamide resistant; C, chloramphenicol resistant; T, tetracycline resistant; S, trimethoprim-sulfamethoxazole resistant. Breakpoints (intermediate and resistant, respectively) according to CLSI are as follows: penicillin G, 0.12 to 1 μg/ml and ≥2 μg/ml; erythromycin A (macrolide), 0.5 μg/ml and ≥ 1 μg/ml; clindamycin (lincosamide), 0.5 μg/ml and ≥ 1 μg/ml; chloramphenicol, not determined and ≥8 μg/ml; tetracycline, 4 μg/ml and ≥8 μg/ml; trimethoprim-sulfamethoxazole, 1/19 μg/ml 2/38 μg/ml, and ≥4/76 μg/ml.