TABLE 3.
Summary of polymorphisms in UPRT-1 intron 1 from T. gondii strains
| Allele type | Strain | Source | UPRT-1 nucleotide at SNP positiona:
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 176 | 197 | 207 | 335 | 385 | 386 | 389 | 409 | 414 | 442 | |||
| I | RH | Human | A | C | C | T | C | C | C | G | G | C |
| GT1 | Goat | A | C | C | T | C | C | C | G | G | C | |
| II | B7 | Sheep | C | T | G | C | T | C | C | T | G | C |
| DEG | Human | C | T | G | C | T | C | C | T | G | C | |
| III | CTG | Cat | C | T | G | C | T | C | C | T | G | C |
| VEG | Human | C | T | G | C | T | C | C | T | G | C | |
| Clinical samples | WU08 | Human | C | T | G | C | T | C | C | T | G | C |
| WU05 | Human | A | C | C | C | C | G | A | G | A | G | |
a
Nucleotides are shown at the numbered positions that contained one or more SNPs. The total intron size is 443 bp, and positions not indicated were identical for all strains. Size is based on the noncoding region including the GT/AC splice site. Biallelic polymorphisms are found in the type strains and WU08, which has a type III genotype. WU05 contains biallelic polymorphisms shared with the clonal types and also contains 4 unique SNPs (bold).