TABLE 3.
Multivariate analysis of the association between plcD interruption and extrathoracic TB after adjusting for the genotypes of plcABC genes and the three host-related risk factors using GEEa
| Variable in the model | Adjusted OR | 95% CI |
|---|---|---|
| plcD genotypes | ||
| plcD wild type | 1.00 | |
| plcD mutant | 3.27 | 1.32-8.14 |
| plcD and adjacent gene mutant group | 1.25 | 0.73-2.14 |
| plcABC genotypes | ||
| plcABC wild type | 1.00 | |
| One of plcABC mutant | 0.93 | 0.34-2.53 |
| Two of plcABC mutant | 1.15 | 0.08-16.01 |
| plcABC all mutant | 0.77 | 0.08-7.27 |
| HIV serological test | ||
| HIV seronegative | 1.00 | |
| HIV seropositive | 5.22 | 1.78-15.23 |
| Unknown | 1.05 | 0.61-1.80 |
| Race/ethnicity | ||
| Non-Hispanic white | 1.00 | |
| Non-Hispanic black | 2.39 | 1.31-4.38 |
| Other | 2.16 | 0.92-5.08 |
| Gender | ||
| Male | 1.00 | |
| Female | 2.46 | 1.52-4.00 |
a
Adjusted OR is adjusted for mutations in other plc genes and the three host-related factors using logistic regression GEE (n = 682).