TABLE 6.
In vitro susceptibilities of non-Candida yeasts to fluconazole and voriconazole as determined by CLSI disk diffusion testing: ARTEMIS DISK Surveillance Program, 2001 to 2003a
Species | Susceptibility
|
|||||
---|---|---|---|---|---|---|
Fluconazoleb
|
Voriconazoleb
|
|||||
n | %S | %R | n | %S | %R | |
Cryptococcus neoformans | 1,281 | 79.1 | 9.8 | 1,266 | 97.2 | 11.7 |
Cryptococcus spp.c | 50 | 68.0 | 16.0 | 50 | 86.0 | 10.0 |
Saccharomyces cerevisiae | 413 | 86.9 | 6.8 | 401 | 94.8 | 3.2 |
Trichosporon spp.d | 291 | 80.8 | 11.3 | 270 | 92.9 | 2.6 |
T. beigelii/T. cutaneum | 80 | 73.8 | 15.0 | 78 | 79.5 | 15.4 |
T. mucoides | 14 | 100.0 | 0.0 | 14 | 100.0 | 0.0 |
T. asahii | 6 | 50.0 | 33.3 | 6 | 66.7 | 33.3 |
Rhodotorula spp.e | 139 | 30.9 | 65.5 | 137 | 43.1 | 51.1 |
Blastoschizomyces capitatus | 55 | 76.4 | 16.4 | 55 | 89.1 | 5.5 |
Pichia spp.f | 27 | 81.5 | 11.1 | 26 | 100.0 | 0.0 |
Hansenula anomala | 13 | 69.2 | 7.7 | 13 | 92.3 | 7.7 |
Isolates obtained from 115 institutions in 35 countries.
Fluconazole and voriconazole disk diffusion testing was performed in accordance with CLSI M44-A. Interpretive breakpoints: S, ≥19 mm (fluconazole), ≥17 mm (voriconazole); R, ≤14 mm (fluconazole), ≤13 mm (voriconazole).
Cryptococcus species other than C. neoformans.
Trichosporon species not otherwise identified.
Rhodotorula species not otherwise identified.
Pichia species not otherwise identified.