TABLE 7.

Voriconazole MICs for Candida spp. calculated from disk zone diameter measurements and MIC versus zone diameter regression plots: comparison with ARTEMIS BMD MIC results^a

Species	Calculated MIC (μg/ml) and %Rb				ARTEMIS BMD MIC (μg/ml) and %Rb,c
	n	50%d	90%d	%R	n	50%d	90%d	%Rb
C. albicans	47,584	0.02	0.09	0.7	2,359	0.007	0.015	1.0
C. glabrata	8,719	0.36	2.08	5.8	607	0.25	1.0	4.0
C. parapsilosis	5,233	0.02	0.16	0.8	439	0.015	0.12	1.0
C. tropicalis	5,643	0.11	0.86	2.4	319	0.06	0.12	1.0
C. krusei	1,996	0.24	0.95	1.7	114	0.25	0.5	0.0
C. lusitaniae	445	0.01	0.12	1.6	42	0.007	0.06	0.0
C. pelliculosa	38	0.09	0.26	0.0	16	0.25	0.5	0.0

^aBMD testing was performed as described in CLSI M27-A2, and disk diffusion testing was performed as described in CLSI M44-A.

^b%R, percent resistant to voriconazole (MIC ≥ 4 μg/ml).

^cData abstracted from Pfaller et al. (24).

^d50% and 90%, MIC encompassing 50% and 90% of isolates tested, respectively.