Table 1.
Clinical Characteristics of TCGA-KIRC, CPTAC -CCRCC and DCC cohorts
| Covariates | Groups | TCGA-KIRC | p | CPTAC-ccRCC | p | DCC | p | |||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| Alive N=207 |
Dead N=101 |
Alive N=140 |
Dead N=27 |
Alive N=66 |
Dead N=49 |
|||||
| Age(mean (SD)) | 59.69 (11.27) |
64.61 (11.69) |
<0.001 | 60.16 (11.86) |
64.11 (11.09) |
0.111 | 60.23 (10.33) | 63.68 (12.50) | 0.120 | |
| Sex, n (%) | Female | 71 (34.3) | 34 (33.7) | 1.000 | 99 (70.7) | 18 (66.7) | 0.849 | 27 (41.5) | 11 (22.4) | 0.052 |
| Male | 136 (65.7) | 67 (66.3) | 41 (29.3) | 9 (33.3) | 38 (58.5) | 38 (77.6) | ||||
| Stage, n (%) | I | 132 (63.8) | 19 (18.8) | <0.0001 | 83 (59.3) | 4 (14.8) | <0.001 | 39 (63.9) | 13 (33.3) | <0.001 |
| II | 20 (9.7) | 8 (7.9) | 13 (9.3) | 3 (11.1) | 9 (14.8) | 3 (7.7) | ||||
| III | 43 (20.8) | 28 (27.7) | 36 (25.7) | 14 (51.9) | 10 (16.4) | 9 (23.1) | ||||
| IV | 12 (5.8) | 46 (45.5) | 8 (5.7) | 6 (22.2) | 3 (4.9) | 14 (35.9) | ||||
| Grade, n (%) | G1 | 7 (3.4) | 0 (0.0) | <0.0001 | 13 (9.3) | 2 (7.4) | 0.004 | 5 (7.9) | 0 (0.0) | 0.076 |
| G2 | 113 (54.6) | 20 (19.8) | 81 (57.9) | 9 (33.3) | 31 (49.2) | 14 (35.9) | ||||
| G3 | 76 (36.7) | 43 (42.6) | 40 (28.6) | 10 (37.0) | 17 (27.0) | 13 (33.3) | ||||
| G4 | 11 (5.3) | 38 (37.6) | 6 (4.3) | 6 (22.2) | 10 (15.9) | 12 (30.8) | ||||
| AUA Risk (Binary), n (%) | Intermediate_high | 33 (55.0) | 30 (76.9) | 0.045 | ||||||
| Low | 27 (45.0) | 9 (23.1) | ||||||||