FIG. 10.
DLP-binding activity of different SA11 NSP4 mutants. Note that all the mutants failed to bind DLPs at low concentration and required 100-fold more protein to bind DLPs equivalent to that bound by 0.001 μg of ΔN72. The C-terminal methionine mutant Hgm15 did not bind DLPs even at high concentration. At high concentration, the DLP-binding activity of Hgm3 is similar to that of ΔN72.