FIG. 4.

IFN-γ inhibits reactivation from latency through the IFN-γ receptor. (A) Ex vivo reactivation. At 28 days postinfection, peritoneal cells from IFN-γR^−/− mice were harvested and assayed for frequency of reactivation by limiting dilution in the presence or absence of 100 U of IFN-γ/ml. Parallel samples were mechanically disrupted (dis.) to determine the presence of persistent virus at the time of plating. n, number of independent experiments.