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IFN-γ does not suppress reactivation of γHV68 through a paracrine effect on infected cells. Ex vivo reactivation is shown. The numbers in the legend indicate the ratios in which the wild-type peritoneal cells were mixed with the IFN-γR−/− peritoneal cells. The concentration of IFN-γ used was 100 U/ml. The statistical significance of the difference between wild-type cells plated in the presence and absence of IFN-γ was P = 0.02.
