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Incubation period of disease following i.p. inoculation of 0- to 1-, 10-, 14-, and 29- to 46-day-old mice with a 10−2 dilution of ME7 scrapie-infected brain homogenate. Shaded symbols represent individual terminally affected mice with a histopathologically confirmed scrapie diagnosis. The numbers of mice surviving to beyond 550 days with a negative histopathological scrapie diagnosis are indicated.
