FIG. 9.
Impact of CCCP treatment of tPMP-1s parental strains upon baseline tPMP-1 susceptibility profiles. Data represent the mean (±SD) of surviving CFU after exposure to various concentrations of tPMP-1 (0 to 2 μg/ml) in the presence or absence of CCCP (100 μM). (A) Data for parental strain ISP479C. *, not significantly different from untreated controls; **, P < 0.0001 versus untreated controls; ***, P < 0.001 versus untreated controls. (B) Data for parental strain SH1000. *, not significantly different from untreated controls; **, P < 0.05 versus untreated controls. Numbers above bars in panels A and B represent the mean fold increases in surviving CFU, comparing CCCP exposures to no-CCCP exposures. These data represent the means of at least two independent assays.