TABLE 2.
Average number of replacements observed and percent genetic distances of the nine pmp genes of C. trachomatis for all 18 serovars and the genovariant Jaa
| Gene | Mean | Within-group means (SE; % change)
|
Between-group means (SE; % change)
|
||||
|---|---|---|---|---|---|---|---|
| Ocular | Genital | LGV | Ocular/genital | Ocular/LGV | Genital/LGV | ||
| pmpA | 4.0 (1.1; 0.1) | 2.8 (1.2; 0.1) | 3.5 (1.2; 0.1) | 0.5 (0.5; <0.1) | 4.2 (1.1; 0.1) | 6.0 (2.0; 0.2) | 4.3 (1.5; 0.2) |
| 2.4 (0.9; 0.2) | 2.8 (1.2; 0.3) | 2.0 (0.9; 0.2) | 0.0 (0.0; 0.0) | 3.1 (1.0; 0.3) | 3.8 (1.6; 0.4) | 1.9 (1.0; 0.1) | |
| pmpB | 29.2 (3.1; 0.6) | 1.2 (0.8; <0.1) | 14.8 (2.4; 0.3) | 16.3 (3.0; 0.3) | 13.4 (2.3; 0.3) | 59.8 (6.9; 1.2) | 57.4 (6.5; 1.1) |
| 24.1 (2.7; 1.4) | 1.2 (0.8; <0.1) | 10.4 (2.0; 0.6) | 12.2 (2.5; 0.7) | 10.5 (2.2; 0.6) | 52.5 (6.9; 3.0) | 49.1 (6.1; 2.8) | |
| pmpC | 26.8 (3.2; 0.5) | 4.5 (1.5; <0.1) | 20.7 (3.2; 0.4) | 5.3 (1.6; 0.1) | 21.5 (3.6; 0.4) | 41.8 (6.5; 0.8) | 40.3 (5.2; 0.8) |
| 20.0 (2.8; 1.1) | 3.0 (1.2; 0.2) | 15.0 (2.7; 0.9) | 4.2 (1.5; 0.2) | 15.3 (2.7; 0.9) | 32.8 (5.7; 1.9) | 30.7 (4.8; 1.8) | |
| pmpD | 12.7 (1.9; 0.3) | 7.0 (1.7; 0.2) | 10.7 (1.7; 0.2) | 1.0 (0.6; <0.1) | 12.0 (2.0; 0.3) | 15.5 (3.4; 0.3) | 17.2 (3.1; 0.4) |
| 7.4 (1.7; 0.5) | 5.3 (1.6; 0.4) | 6.0 (1.5; 0.4) | 0.0 (0.0; 0.0) | 7.2 (1.6; 0.5) | 11.0 (3.2; 0.7) | 9.5 (2.8; 0.6) | |
| pmpE | 67.6 (4.9; 2.4) | 4.3 (1.4; 0.2) | 49.2 (4.4; 1.8) | 4.5 (1.4; 0.2) | 108.4 (8.1; 3.9) | 116.0 (9.4; 4.2) | 49.5 (4.9; 1.8) |
| 24.5 (2.7; 2.7) | 2.7 (1.1; 0.3) | 15.8 (2.2; 1.7) | 1.5 (0.8; 0.2) | 39.5 (5.1; 4.3) | 46.0 (6.2; 5.0) | 18.6 (2.9; 2.0) | |
| pmpF | 215.5 (8.1; 7.0) | 3.0 (1.4; 0.1) | 102.1 (5.7; 3.3) | 0.0 (0.0; 0.0) | 237.4 (11.9; 7.7) | 418.0 (18.5; 13.5) | 320.1 (14.6; 10.3) |
| 71.4 (4.9; 6.9) | 1.8 (1.1; 0.2) | 34.3 (3.4; 3.3) | 0.0 (0.0; 0.0) | 74.7 (7.2; 7.3) | 140.5 (11.0; 13.7) | 108.6 (8.8; 10.6) | |
| pmpG | 27.0 (2.9; 0.9) | 3.5 (1.4; 0.1) | 9.1 (1.9; 0.3) | 2.0 (1.0; <0.1) | 14.2 (3.1; 0.5) | 59.8 (6.9; 2.0) | 57.1 (6.6; 1.9) |
| 12.0 (2.1; 1.2) | 2.8 (1.2; 0.3) | 4.0 (1.2; 0.4) | 2.0 (1.0; 0.2) | 6.6 (1.9; 0.7) | 25.8 (5.0; 2.6) | 24.9 (4.8; 2.5) | |
| pmpH | 100.6 (6.0; 3.3) | 1.5 (0.8; <0.1) | 30.9 (2.4; 1.0) | 2.7 (1.3; <0.1) | 131.6 (10.3; 4.4) | 189.1 (12.4; 6.3) | 170.2 (11.1; 5.7) |
| 26.8 (3.02; 2.7) | 0.0 (0.0; 0.0) | 8.3 (1.3; 0.8) | 1.3 (0.9; 0.1) | 33.6 (5.1; 3.4) | 59.3 (7.1; 6.0) | 43.9 (5.9; 4.4) | |
| pmpI | 14.7 (2.4; 0.6) | 5.7 (1.9; 0.2) | 9.2 (1.9; 0.4) | 0.5 (0.5; <0.1) | 14.4 (3.0; 0.6) | 21.8 (4.6; 0.8) | 22.3 (4.2; 0.9) |
| 6.3 (1.5; 0.7) | 1.0 (0.7; 0.1) | 4.8 (1.3; 0.6) | 0.0 (0.0; 0.0) | 8.0 (2.3; 0.9) | 7.5 (2.5; 0.9) | 7.5 (2.2; 0.9) | |
a
Upper-row data are nucleotide substitutions; lower-row data are amino acid substitutions.