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Stability of TFO-P and conjugate TFO-CPT(10) in cell medium. The 5′-end-radiolabeled oligonucleotides (left panel) were incubated in cell culture medium (DMEM containing 10% fetal bovine serum) at 37°C. Aliquots were removed after 24 h (central panel) or 72 h (right panel) and analyzed on a 20% denaturing gel.
