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. 2005 Nov 8;392(Pt 1):13–20. doi: 10.1042/BJ20050515

Figure 3. Crystal structure of the human Notch 1 ANK domain.

Figure 3

(A) Both molecules in the asymmetric unit are shown. Repeats 2–7 are individually coloured starting with blue at the N-terminus and ending with red at the C-terminus. (B) Notch ANK domains pack end-to-end in the crystal lattice. A symmetry-related ANK domain is shown with both ANK chains in the asymmetric unit. (C) Residues involved in the formation of crystal contacts between successive domains in the crystal. Figures are rotated from their original position in (B) to better show the contacts. Residues involved in forming the contacts were identified using the protein–protein interaction server (http://www.biochem.ucl.ac.uk/bsm/PP/server/). The Figure was created using PyMOL.