Table 2. Number of highly expressed PS in different subtypes of human ALL and AML.
T-ALL
|
B-ALL
|
AML
|
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Clusters | n | +MLL | –MLL | +MLL | BCR/ABL | E2A/PBX1 | TEL/AML1 | HD50 | Others | +MLL | PML/RARα | AML1/ETO | CBFβ/MYH11 | M7 | Others |
Hematopoietic | 1,038 | 286 (0) | 286 (1) | 265 (0) | 302 (0) | 249 (1) | 300 (0) | 278 (0) | 294 (0) | 318 (1) | 244 (0) | 277 (0) | 329 (0) | 281 (0) | 306 (0) |
Nonhematopoietic | 1,450 | 51 (10) | 33 (3) | 50 (9) | 51 (5) | 53 (9) | 49 (13) | 45 (6) | 44 (4) | 44 (4) | 53 (6) | 41 (1) | 35 (2) | 55 (5) | 30 (1) |
n, total number of PS in all H or NH clusters. Values in parentheses are the number of PS that are highly expressed in cells from different leukemia subtypes but not in normal hematopoietic cells.