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. 2026 Apr 13;24:312. doi: 10.1186/s12916-026-04842-8

Table 2.

Results of survival analysis for all three cohorts

Sample size Outcome (n) 5-year survival probability (%) Hazard ratio (95% confidence interval) Log-rank test P value E-value
Obesity
All obesity-related cancers
 Reference 2,555,462 45,582 97.2 1.00 (1.00–1.00)
 Obesity 2,555,462 45,370 97.2 0.99 (0.98, 1.01) 3.1 0.08 1.00
Traditional obesity-related cancers
 Reference 2,555,462 37,674 97.7 1.00 (1.00–1.00)
 Obesity 2,555,462 40,557 97.5 1.07 (1.05, 1.09) 89.0 < 0.01 1.34
Type 2 diabetes
All obesity-related cancers
 Reference 290,937 8589 95.6 1.00 (1.00–1.00)
 Type 2 diabetes 290,937 11,207 94.5 1.27 (1.23, 1.31) 277.8 < 0.01 1.87
Traditional obesity-related cancers
 Reference 290,937 7055 96.4 1.00 (1.00–1.00)
 Type 2 diabetes 290,937 9775 95.2 1.35 (1.31, 1.39) 368.5 < 0.01 2.04
Obesity and type 2 diabetes
All obesity-related cancers
 Reference 609,619 16,302 96.2 1.00 (1.00–1.00)
 Obesity and type 2 diabetes 609,619 21,766 95.1 1.30 (1.27, 1.32) 627.8 < 0.01 1.92
Traditional obesity-related cancers
 Reference 609,619 13,275 96.9 1.00 (1.00–1.00)
 Obesity and type 2 diabetes 609,619 20,187 95.5 1.48 (1.45, 1.51) 1237.2 < 0.01 2.32