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. 2026 May 20;24:321. doi: 10.1186/s12916-026-04906-9

Table 4.

Associations between intellectual disability and outcomes among those diagnosed with bowel cancer

No ID ID RR (95% CI)
Route to diagnosis N / total diagnosesa N / total diagnosesa
Screening 10 / 349 (2.9%) 580 / 5571 (10.4%) 0.27 (0.14-0.50)
Urgent suspected cancer referral 72 / 349 (20.6%) 1896 / 5571 (34.0%) 0.62 (0.50-0.76)
Emergency presentation 136 / 349 (39.0%) 1240 / 5571 (22.3%) 1.76 (1.52-2.02)
Diagnosis recorded on date of death N / total diagnoses N / total diagnoses
60 / 6085 (1.0%) 16 / 381 (4.2%) 5.08 (2.92-8.84)
Curative surgery within 6 months N / total with non-metastatic diseaseb N / total with non-metastatic diseaseb
1813 / 2218 (81.7%) 95 / 118 (80.5%) 0.98 (0.79-1.19)
SACT within 6 months for metastatic disease N / total with metastatic diseaseb,c N / total with metastatic diseaseb,c
241 / 476 (50.6%) <5 / 34 0.15 (0.05-0.46)
Stage at diagnosis N N
Stage I 736 (12.1%) 36 (9.4%)
Stage II 979 (16.1%) 53 (13.9%)
Stage III 1179 (19.4%) 69 (18.1%)
Stage IV 1178 (19.4%) 89 (23.4%) 1.25 (1.01-1.56)d
Unknown 2013 (33.1%) 134 (35.2%) 1.08 (0.91-1.29)e

ID intellectual disability, FIT faecal immunochemical test, FOB faecal occult blood test, RR risk ratio, CI confidence interval, SACT systemic anticancer therapy

aWith recorded route to diagnosis

bWith required follow-up

cFrom 2014 due to availability of SACT data

dStage 4 vs. stages 1–3

eKnown stage vs. unknown stage