Table 3.

Factor analysis of risk factors for death in M-HLH.

Factors	Univariate analysis			Multivariate analysis
	HR	95%CI	P value	HR	95%CI	P value
Age < 10 years	0.363	0.131-1.001	0.05
PLT ≥ 100×109/L	0.17	0.022-1.286	0.086
SF ≤ 5000 ng/mL	0.219	0.081-0.59	0.003
AST < 80 U/L	0.358	0.115-1.111	0.075
LDH < 500 U/L	0.239	0.054-1.054	0.059
The malignancies' direct treatment	0.506	0.237-1.084	0.08
CR at the final follow-up	0.036	0.01-0.138	< 0.001	0.036	0.01-0.138	<0.001
CR at 4 weeks	0.149	0.042-0.529	0.003

AST, Aspartate aminotransferase; LDH, Lactate dehydrogenase; SF, Serum ferritin; PLT, Platelet count.