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. 2026 Mar 25;15(4):332. doi: 10.21037/tcr-2026-1-0320

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Nodal response and survival outcomes. (A) Changes in short-axis diameter of cervical lymph nodes from baseline to post-IC in all patients (n=214). (B-E) Kaplan-Meier estimates of PFS (B), OS (C), LRRFS (D), and DMFS (E) in the de-escalation cohort (n=60). (F) Post-IC nodal CR was associated with better PFS compared to non-CR in all patients (n=214). Tumor response was assessed according to RECIST v1.1. CI, confidence interval; CR, complete response; DMFS, distant metastasis-free survival; HR, hazard ratio; IC, induction chemotherapy; LRRFS, locoregional relapse-free survival; OS, overall survival; PFS, progression-free survival; RECIST, Response Evaluation Criteria in Solid Tumors.