Table 2.

Comparison of TRIM72/MG53 and related hormonal and metabolic parameters between PCOS and control groups.

Variable	PCOS(Median [IQR])	Control (Median [IQR])	p
TRIM72/MG53 (pg/mL)	124.40 [104.25–202.15]	206.40 [131.62–316.57]	0.001
LH (IU/L)	6.55 [4.70–9.14]	4.94 [3.73–6.17]	< 0.001
LH/FSH ratio	1.04 [0.80–1.43]	0.67 [0.51–0.95]	< 0.001
Total testosterone (µg/L)	0.32 [0.23–0.38]	0.21 [0.17–0.29]	< 0.001
Sex hormone-binding globulin (SHBG, nmol/L)	58.10 [38.27–70.33]	75.00 [57.70–90.28]	0.001
Anti-Müllerian hormone (AMH, ng/mL)	6.77 [5.64–9.73]	3.65 [1.66–5.02]	< 0.001
HOMA-IR	2.46 [1.87–3.13]	2.04 [1.36–2.50]	0.003
ALT (U/L)	16.00 [13.00–23.00]	14.00 [11.00–19.00]	0.016
Glucose (mg/dL) (mean ± sd)	91.09 ± 7.35	86.56 ± 10.93	0.019
Insulin (mU/L)	11.21 [8.00–14.20]	9.95 [6.18–12.17]	0.030
FSH (IU/L)	6.22 [5.52–7.17]	6.67 [5.71–8.57]	0.040
LDL cholesterol (mg/dL)	102.50 [83.00–125.00]	97.50 [78.75–106.25]	0.080
Erythrocyte sedimentation rate (mm/h)	7.00 [4.00–12.25]	6.00 [2.00–9.00]	0.122
AST (U/L)	17.00 [15.00–19.00]	15.00 [14.00–19.00]	0.152
Total cholesterol (mg/dL)	179.50 [148.75–207.50]	173.00 [152.75–196.00]	0.298
HDL cholesterol (mg/dL)	55.50 [47.75–62.25]	56.50 [48.00–65.25]	0.418
C-reactive protein (CRP, mg/L)	4.00 [1.00–8.00]	3.00 [1.00–5.33]	0.433
Thyroid-stimulating hormone (TSH, mIU/L)	1.35 [1.16–1.96]	1.48 [1.18–2.09]	0.457
Prolactin (ng/mL)	11.29 [8.19–15.44]	10.50 [8.22–14.07]	0.740
Triglycerides (mg/dL)	93.50 [66.25–121.75]	88.00 [60.50–131.25]	0.782

Data are presented as mean ± SD for normally distributed variables and as median [IQR] for non-normally distributed variables. Between-group comparisons were performed using Welch’s t-test for normally distributed variables and the Mann–Whitney U test for non-normally distributed variables. P < 0.05 was considered statistically significant.