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. 2026 Apr 13;16:15753. doi: 10.1038/s41598-026-48800-z

Table 4.

Multiple linear regression analysis showing independent predictors of circulating MG53 (TRIM72) levels.

Variable B SE t p-value 95% CI
HDL cholesterol 0.48 2.32 0.21 0.836  − 4.11 – 5.07
Sex hormone-binding globulin (SHBG) 2.52 0.96 2.63 0.010 0.62 – 4.42
C-reactive protein  − 3.62 5.52  − 0.66 0.513  − 14.56 – 7.31
Hirsutism  − 186.53 77.98  − 2.39 0.018  − 340.94 – − 32.11
PCOS 80.32 96.30 0.83 0.406  − 110.37 – 271.02
Maximum Ovarian Volume 3.13 8.95 0.35 0.727  − 14.59 – 20.85
Ovarian Follicle Count  − 34.10 16.99  − 2.01 0.047  − 67.74 – − 0.46
Age 9.09 6.27 1.45 0.150  − 3.32 – 21.50
Body Mass Index 10.82 7.35 1.47 0.143  − 3.73 – 25.37

Model statistics: n = 128, R2 = 0.182, adjusted R2 = 0.123, F(9,118) = 3.10, p(model) = 0.003. Regression coefficients (B) are presented with standard errors and 95% confidence intervals.

Age and BMI were included as covariates to control for potential demographic and anthropometric confounding.