Figure 5.

Treatment with a CCR3 antagonist prevents the increase in eosinophils around airway nerves after antigen challenge. Airway nerves (arrows) were stained black with antibody against PGP 9.5, and eosinophils were stained red with chromotrope 2R in control and antigen-challenged animals and in antigen-challenged animals treated with CCR3 antagonist. Numbers under the panels refer to the percentage of eosinophils (mean ± SEM; n = 5–7) in contact with airway nerves. The scale bar of 50 μm applies to all panels except the one in the upper right, where it equals 20 μm.