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. 2026 Jun;32(6):660–669. doi: 10.18553/jmcp.2026.32.6.660

TABLE 2.

Adjusted Odds of Treatment Persistence and Adherence According to Demographic Characteristics and Comorbidities

Characteristic Persistence from months 1 to 12 Adherence from months 1 to 12
Odds ratio 95% CI Odds ratio 95% CI
Age younger than 30 years Reference
31-40 years 1.22 0.51-2.93 0.84 0.34-2.06
41-50 years 0.82 0.34-1.95 0.57 0.24-1.39
51-60 years 0.88 0.36-2.18 0.55 0.22-1.40
>60 years 1.24 0.46-3.35 0.76 0.28-2.10
Male sex Reference
Female sex 0.32 0.14-0.75 0.33 0.14-0.77
Race
 White or Caucasian Reference
 Black or African American 1.10 0.70-1.74 1.19 0.76-1.89
 Othera 0.88 0.36-2.18 0.95 0.39-2.35
Ethnicity
 Not Hispanic or Latino Reference
 Hispanic or Latino 2.88 0.95-8.71 2.76 0.92-8.29
Comorbidities
 HTN (present vs absent) 1.23 0.77-1.95 1.06 0.67-1.67
 HLD (present vs absent) 0.83 0.53-1.29 1.04 0.67-1.61
 T2DM (present vs absent) 0.78 0.41-1.47 0.83 0.44-1.56
 CVD (present vs absent) 0.79 0.41-1.53 0.98 0.50-1.89
 MDD (present vs absent) 0.79 0.51-1.2 0.81 0.53-1.25
a

Asian, American Indian or Alaskan Native, and all other races specified.

CVD = cardiovascular disease; HLD = hyperlipidemia; HTN = hypertension; MDD = major depressive disorder; T2DM = type 2 diabetes.