TABLE 4.

Comparison of All-Cause Health Care Costs Between Patients With and Without Recurrence

All-cause health care costs	Resected		Unresected
	Adjusted monthly cost differencea	95% CI	Adjusted monthly cost differencea	95% CI
Total costs, 2023 USD	3,831	(2,319-5,360)	4,730	(3,611-5,870)
Medical costs	3,732	(2,232-5,247)	4,649	(3,541-5,779)
Part D pharmacy costs	92	(−11-198)	340	(17-636)

^a Monthly cost differences and P values were estimated using univariable generalized linear models with a Tweedie distribution (a compound Poisson-gamma distribution) and log-link function. The adjusted models controlled for age at index date, sex (reference: male), race (reference: White), region (reference: west), Charlson comorbidity index, disease stage at diagnosis (reference: stage III), cancer site (reference: oropharynx), primary treatment (reference: surgery only), and corresponding costs during the baseline period. A monthly cost difference greater than 0 indicates patients with recurrence incurred more health care costs than patients without recurrence.

USD = United States dollars.