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. 2026 May 22;9(8):e202603659. doi: 10.26508/lsa.202603659

Figure 2. Sample-level multi-omics landscape visualizations with OncoPrint and Circos plots.

Figure 2.

(A, B) OncoPrint shows gene-level multi-omics alterations across samples, combining somatic mutations, RNA and protein expression, and CNV data. Clinical annotations appear above the plot. Data types are encoded by color and shape. Users can adjust thresholds for expression and CNV to refine the view; and (B) Circos plot displays a circular view of omics alterations in a selected sample. Concentric rings represent somatic mutations, RNA expression, DNA methylation, proteomics, CNVs, and structural variants. The plot adapts to the uploaded data types available for each sample.