Table 1.
Survival analysis of lncRNAs
| S.No. | Associated genes | Survival | Patient No. | p-value | HR | CI | Low expression cohort (months) | High expression cohort (months) |
|---|---|---|---|---|---|---|---|---|
| 1 | FBXL19-AS1 | OS | 1411 | 0.0021 | 1.26 | 1.09–1.46 | 88 | 60 |
| OS+LUAD | 672 | 0.0015 | 1.47 | 1.16–1.87 | 127 | 87.7 | ||
|
OS+LUAD +Smoker |
131 | 0.67 | 1.11 | 0.69–1.8 | 46 | 43.07 | ||
|
OS+LUAD +Smoker+Males |
162 | 0.48 | 0.81 | 0.45–1.45 | 41.4 | 54.17 | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.33 | 1.57 | 0.63–3.92 | – | – | ||
| 2 | HCP5 | OS | 1411 | 0.0029 | 0.83 | 0.74–0.94 | 62.2 | 76 |
| OS+LUAD | 672 | 0.034 | 0.83 | 0.7–0.99 | 74 | 86 | ||
|
OS+LUAD +Smoker |
546 | 0.099 | 0.8 | 0.62–1.04 | 78 | 80 | ||
|
OS+LUAD +Smoker+Males |
319 | 0.17 | 0.79 | 0.55–1.11 | 78 | 80 | ||
|
OS+LUAD+ Smoker+Females |
227 | 0.35 | 0.83 | 0.56–1.23 | 71 | 95 | ||
| 3 | HMMR-AS1 | OS | 1411 | 0.51 | 1.05 | 0.91–1.22 | 77.77 | 73.3 |
| OS+LUAD | 672 | 0.2 | 1.17 | 0.92–1.48 | 108 | 90 | ||
|
OS+LUAD +Smoker |
231 | 0.44 | 0.83 | 0.51–1.35 | 42 | 54.17 | ||
|
OS+LUAD +Smoker+Males |
162 | 0.64 | 0.87 | 0.49–1.55 | 44.83 | 43.07 | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.48 | 1.38 | 0.56–3.42 | 91 | 68 | ||
| 4 | HOXA11-AS | OS | 1411 | 0.019 | 1.19 | 1.03–1.38 | 86.27 | 63.03 |
| OS+LUAD | 672 | 0.00043 | 1.53 | 1.21–1.95 | 119.87 | 91 | ||
|
OS+LUAD +Smoker |
231 | 0.45 | 1.21 | 0.74–1.96 | 47.77 | 42 | ||
|
OS+LUAD +Smoker+Males |
162 | 0.67 | 1.13 | 0.63–2.03 | 47.77 | 41.4 | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.6 | 1.27 | 0.52–3.13 | 57 | 40.21 | ||
| 5 | LINC00460 | OS | 1411 | 0.75 | 0.98 | 0.84–1.13 | 76 | 72.33 |
| OS+LUAD | 672 | 0.74 | 0.96 | 0.76–1.22 | 99 | 107 | ||
|
OS+LUAD +Smoker |
231 | 0.92 | 0.98 | 0.6–1.58 | 41.4 | 47.77 | ||
|
OS+LUAD +Smoker+Males |
162 | 0.37 | 0.77 | 0.43–1.37 | 38.1 | 48 | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.37 | 1.52 | 0.61–3.79 | 68 | 35 | ||
| 6 | LINC00467 | OS | 1411 | 0.0014 | 0.79 | 0.68–0.91 | 63 | 92.97 |
| OS+LUAD | 672 | 0.00014 | 0.63 | 0.49–0.8 | 79.87 | 125.77 | ||
|
OS+LUAD +Smoker |
231 | 0.014 | 0.54 | 0.33–0.89 | 36 | 54.17 | ||
|
OS+LUAD +Smoker+Males |
162 | 0.027 | 0.51 | 0.28–0.94 | – | – | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.19 | 0.54 | 0.21–1.38 | – | – | ||
| 7 | MAFG-AS1 | OS | 1411 | 0.086 | 1.14 | 0.98–1.32 | 87.7 | 68.1 |
| OS+LUAD | 672 | 0.00016 | 1.59 | 1.25–2.02 | 119.87 | 74 | ||
|
OS+LUAD +Smoker |
231 | 0.016 | 1.83 | 1.11–3.03 | – | – | ||
|
OS+LUAD +Smoker+Males |
162 | 0.084 | 1.69 | 0.93–3.07 | 54.17 | 38 | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.02 | 3.15 | 1.13–8.76 | 91 | 19 | ||
| 8 | MALAT1 | OS | 1411 | 0.053 | 0.86 | 0.74–1.74 | 68 | 88.7 |
| OS+LUAD | 672 | 0.67 | 0.95 | 0.75–1.21 | 103 | 108 | ||
|
OS+LUAD +Smoker |
231 | 0.61 | 0.88 | 0.54–1.43 | 41.4 | 48 | ||
|
OS+LUAD +Smoker+Males |
162 | 0.19 | 0.68 | 0.38–1.22 | 38.1 | 52 | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.34 | 1.55 | 0.62–3.86 | 68 | 37 | ||
| 9 | SBF2-AS1 | OS | 1411 | 0.0013 | 1.27 | 1.1–1.47 | 92.63 | 63.4 |
| OS+LUAD | 672 | 0.26 | 1.15 | 0.9–1.46 | 112.67 | 89 | ||
|
OS+LUAD +Smoker |
231 | 0.34 | 1.27 | 0.78–2.06 | 47.63 | 42 | ||
|
OS+LUAD +Smoker+Males |
162 | 0.091 | 1.65 | 0.92–2.97 | 63 | 41.4 | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.86 | 1.09 | 0.44–2.68 | 47.63 | 57 | ||
| 10 | SNHG6 | OS | 1411 | 1e-06 | 1.45 | 1.25–1.68 | 91 | 57 |
| OS+LUAD | 672 | 0.033 | 1.31 | 1.02–1.67 | 125.77 | 95.07 | ||
|
OS+LUAD +Smoker |
231 | 0.33 | 1.27 | 0.78–2.07 | 47.77 | 38.1 | ||
|
OS+LUAD +Smoker+Males |
162 | 0.72 | 1.11 | 0.62–1.99 | 44.83 | 43.07 | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.31 | 1.62 | 0.63–4.16 | 57 | 34.6 | ||
| 11 | TMPO-AS1 | OS | 1411 | 7.2e-08 | 1.5 | 1.29–1.74 | 99.43 | 52.97 |
| OS+LUAD | 672 | 4.1e-10 | 2.16 | 1.69–2.76 | 133.57 | 63 | ||
|
OS+LUAD +Smoker |
231 | 0.00066 | 2.34 | 1.41–3.88 | – | – | ||
|
OS+LUAD +Smoker+Males |
162 | 0.0046 | 2.33 | 1.28–4.25 | – | – | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.016 | 3.13 | 1.18–8.29 | – | – | ||
| 12 | TTN-AS1 | OS | 1411 | 0.00039 | 0.76 | 0.66–0.89 | 63 | 92.63 |
| OS+LUAD | 672 | 2.9e-05 | 0.59 | 0.46–0.76 | 76 | 117.33 | ||
|
OS+LUAD +Smoker |
231 | 0.0087 | 0.51 | 0.31–0.85 | – | – | ||
|
OS+LUAD +Smoker+Males |
162 | 0.0088 | 0.44 | 0.24–0.83 | – | – | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.39 | 0.67 | 0.27–1.67 | 37 | 47.63 | ||
| 13 | WDFY3-AS2 | OS | 1411 | 1.8e-11 | 0.6 | 0.52–0.7 | 53 | 104 |
| OS+LUAD | 672 | 4.1e-07 | 0.53 | 0.41–0.68 | 69.93 | 133.57 | ||
|
OS+LUAD +Smoker |
231 | 0.0095 | 0.52 | 0.31–0.86 | – | – | ||
|
OS+LUAD +Smoker+Males |
162 | 0.3 | 0.74 | 0.41–1.32 | 38.1 | 47.77 | ||
|
OS+LUAD+ Smoker+Females |
69 | 0.007 | 0.25 | 0.08–0.74 | – | – | ||
| 14 | ZFPM2-AS1 | OS | 2166 | 3.6e-07 | 0.73 | 0.65–0.83 | 54 | 81 |
| OS+LUAD | NA | |||||||
|
OS+LUAD +Smoker | ||||||||
|
OS+LUAD +Smoker+Males | ||||||||
|
OS+LUAD+ Smoker+Females | ||||||||