Table 3.
Patients characteristics
| All patients n = 166 |
Group 1 pre-SOP n = 50 |
Group 2 post-SOP n = 116 |
SMD | |
|---|---|---|---|---|
| Age at diagnosis, median (IQR) | 62 (52, 74) | 62 (52, 76) | 62 (52, 74) | 0.130 |
| Gender | 0.109 | |||
| Male, n (%) | 80 (48.2) | 26 (52.0) | 54 (46.6) | |
| Female, n (%) | 86 (51.8) | 24 (48.0) | 62 (53.4) | |
| Comorbidities | 0.459 | |||
| None, n (%) | 102 (61.4) | 28 (56.0) | 74 (63.8) | |
| Autoimmune disease, n (%) | 2 (1.2) | 1 (2.0) | 1 (0.9) | |
| COPD, n (%) | 8 (4.8) | 1 (2.0) | 7 (6.0) | |
| Diabetes mellitus, n (%) | 12 (7.2) | 7 (14.0) | 5 (4.3) | |
| Cardiovascular disease, n (%) | 6 (3.6) | 1 (2.0) | 5 (4.3) | |
| Liver cirrhosis, n (%) | 11 (6.6) | 3 (6.0) | 8 (6.9) | |
| Renal insufficiency, n (%) | 3 (1.8) | 1 (2.0) | 2 (1.7) | |
| Tumour disease, n (%) | 22 (13.3) | 8 (16.0) | 14 (12.1) | |
| Indication for EVD | 0.397 | |||
| Stroke, n (%) | 6 (3.6) | 3 (6.0) | 3 (2.6) | |
| Brain tumour, n (%) | 19 (11.4) | 4 (8.0) | 15 (12.9) | |
| Hydrocephalus, n (%) | 2 (1.2) | 0 (0) | 1 (1.7) | |
| ICH, n (%) | 27 (16.3) | 6 (12.0) | 21 (18.1) | |
| ICH with intraventricular extension, n (%) | 17 (10.2) | 6 (12.0) | 11 (9.5) | |
| IVH, n (%) | 3 (1.8) | 1 (2.0) | 2 (1.7) | |
| SAH, n (%) | 61 (36.7) | 22 (44.0) | 39 (33.6) | |
| TBI, n (%) | 31 (18.7) | 8 (16.0) | 23 (19.8) | |
| SAPS II-Score at admission, median (IQR) | 37 (32, 46) | 39 (30, 55) | 37 (32, 43) | 0.360 |
| SOFA-Score at admission, median (IQR) | 8 (4, 10) | 8 (4, 10) | 8 (4, 10) | 0.089 |
Table rows displayed in bold indicates events with a higher incidence in Group 1 (pre-SOP)
While age, gender, and SOFA score at admission showed negligible differences in SMD calculation (SMD < 0.13), small-to-medium imbalances were observed in comorbidities (SMD = 0.459), indication for EVD (SMD = 0.397) and SAPS II score (SMD = 0.360)
Abbreviations: COPD chronic obstructive pulmonary disease, CSF cerebrospinal fluid, EVD external ventricular drainage, ICH Intracerebral haemorrhage, IQR interquartile range, IVH intraventricular haemorrhage, SAB subarachnoid haemorrhage, SAPS Simplified Acute Physiology Score, SMD Standardized Mean Difference, SOFA Sequential Organ Failure Assessment Score, TBI traumatic brain injury, n number