Table 7.
SOP adherence of the treatment team
| All patients n = 166 |
Group 1 pre-SOP n = 50 |
Group 2 post-SOP n = 116 |
|
|---|---|---|---|
| 1 st CSF examinations, n (%) | 100 (60.2) | 27 (54.0) | 73 (62.9) |
| 2nd CSF examinations, n (%) | 112 (67,5) | 31 (62.0) | 81 (69.8) |
| 3rd CSF examinations, n (%) | 43 (25.9) | 16 (32.0) | 27 (23.3) |
| Preoperative antibiotic prophylaxis, | |||
| n (%) | 144 (86.7) | 38 (76.0) | 106 (91.4) |
| Empirical antibiotic therapy, n (%) | 29 (17.5) | 14 (28.0) | 15 (12.9) |
| Empirical antibiotic therapy | All patients | Group 1 pre-SOP | Group 2 pre-SOP |
| n = 29 | n = 14 | n = 15 | |
| Adjustment after pathogen detection, n (%) | 11 (37.9) | 5 (35.7) | 4 (26.7) |
| Termination in not-confirmed ventriculitis, n (%) | 2 (6.7) | 0 | 2 (13.3) |
| No adjustment, n (%) | 3 (10.0) | 2 (14.3) | 1 (6.7) |
The adherence of the treatment team to the SOP was analyzed regarding the following key aspects: frequency of csf sampling, administration of antibiotic prophylaxis prior EVD insertion, initiation of empirical antibiotic therapy based on the algorithm, adjustment of antibiotic therapy according to follow-up investigations and premature discontinuation of antibiotic therapy in not-confirmed ventriculitis or adjustment of antibiotic therapy after pathogen identification
Abbreviations: CSF cerebrospinal fluid, SOP standard operation procedure, n number