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. 1982 Apr;46(2):209–211.

Cell mediated immune response in miniature Sinclair swine bearing cutaneous melanomas.

D H Jones, M S Amoss Jr
PMCID: PMC1320283  PMID: 7093814

Abstract

Miniature Sinclair swine bearing cutaneous melanomas and nonmelanoma bearing littermate controls were tested for lymphocyte blastogenic response in a microculture assay. Lymphocytes were assayed for 3H-thymidine incorporation following stimulation with concanavalin A, phytohemagglutinin or pokeweed mitogen. Treatment with all mitogens revealed a significantly (p less than 0.05) reduced proliferative capacity in melanoma swine as compared to littermate controls. These results lend further support for the use of miniature Sinclair swine as a research model for human melanoma.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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