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. 2026 May 13;15(10):774. doi: 10.3390/biology15100774
AD Alzheimer’s disease
AMPK AMP-activated protein kinase
ANLS Astrocyte–neuron lactate shuttle
Arg1 Arginase 1
ATM Adipose tissue macrophage
ATP Adenosine triphosphate
BCAP B-cell adapter for PI3K
BCL2 B-cell lymphoma 2
cAMP Cyclic adenosine monophosphate
CBP CREB-binding protein
ccRCC Clear cell renal cell carcinoma
CoA Coenzyme A
CRC Colorectal cancer
FOXO1 Forkhead box protein O1
GLO1 Glyoxalase I
GLO2 Glyoxalase II
Glis1 GLIS family zinc finger 1
GPCR G-protein-coupled receptor
GPR81 G-protein-coupled receptor 81
GPR132 G-protein-coupled receptor 132
GSK3β Glycogen synthase kinase 3 beta
HAT Histone acetyltransferase
HCAR Hydroxy-carboxylic acid receptor
HCC Hepatocellular carcinoma
HDAC Histone deacetylase
HFD High-fat diet
HIF Hypoxia-inducible factor
HIF-1α Hypoxia-inducible factor 1-alpha
HMGB1 High mobility group box 1
IDH3G Isocitrate dehydrogenase 3 gamma
IFNγ Interferon-gamma
IL-6 Interleukin-6
IL-8 Interleukin-8
iPSC Induced pluripotent stem cell
Kla Lysine lactylation
LCSC Liver cancer stem cell
LDH Lactate dehydrogenase
LDHA Lactate dehydrogenase A
LGSH Lactoylglutathione
LINC00152 Long intergenic non-protein coding RNA 152
lncRNA Long non-coding RNA
LPS Lipopolysaccharide
MCT Monocarboxylate transporter
MMP-2 Matrix metallopeptidase-2
NAD+ Nicotinamide adenine dinucleotide
NADH Nicotinamide adenine dinucleotide (reduced)
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells
OXPHOS Oxidative phosphorylation
P300 Histone acetyltransferase p300 (EP300)
PDC Pyruvate dehydrogenase complex
PDGFRβ Platelet-derived growth factor receptor beta
PDH Pyruvate dehydrogenase
PER1 Period circadian regulator 1
PI3K Phosphoinositide 3-kinase
PKA Protein kinase A
PKM Pyruvate kinase M
PKM2 Pyruvate kinase M2
PRR Pattern recognition receptor
PTM Post-translational modification
SDHA Succinate dehydrogenase complex flavoprotein subunit A
SirT Sirtuin
STAT3 Signal transducer and activator of transcription 3
T3SS Type III secretion system
TCA Tricarboxylic acid cycle
TGFβ2 Transforming growth factor beta 2
TLR Toll-like receptor
TNF-α Tumor necrosis factor alpha
TP53 Tumor protein p53
VEGFA Vascular endothelial growth factor A
VHL Von Hippel–Lindau
YTHDF2 YTH N6-methyladenosine RNA binding protein 2
YY1 Yin Yang 1