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. 2026 May 9;18(5):584. doi: 10.3390/pharmaceutics18050584
8-OHdG 8-hydroxy-2′-deoxyguanosine
acNPs Acid-activated biodegradable nanoparticles
ALT/AST Alanine/aspartate aminotransferase
AMLN Amylin liver NASH diet
APAP Acetaminophen
Au Gold (nanoparticles)
BELNs Blueberry-derived exosome-like nanoparticles
BMI Body mass index
Cap-LNPs Capsaicin-lignin nanoparticles
CeO2 Cerium oxide
CCl4 Carbon tetrachloride
DAMPS Damage-associated molecular patterns
CDD Choline-deficient diet
CD-HFD Choline-deficient high-fat diet
CMNs Cell-membrane nano-particles
CK Compound K (
DBZ Dibenzazepine (PEGylated bilirubin NPs)
DSS Dextran sulfate sodium
EGF Epidermal growth factor
Et (chronic) Chronic ethanol exposure
ER stress Endoplasmic reticulum stress
EASD European Association for the Study of Diabetes
EASL European Association for the Study of the Liver
EASO European Association for the Study of Obesity
ECM Extracellular matrix
FA Fatty acids
FFA Free fatty acids
FXR Farnesoid X receptor;
GalNAc N-acetylgalactosamine
GLP-1 Glucagon-like peptide-1
GSH Glutathione
HCC Hepatocellular carcinoma
H-VLNs Honey vesicle-like nanoparticles
Hep@PGEA Hepatocyte-targeted poly(glycidyl methacrylate-ethanolamine) vector
HFD High-fat diet
HFF High-fat/high-fructose diet
HFHF High-fat/high-fructose diet
HFCMCD High-fat/high-cholesterol/methionine- and choline-deficient diet
HGF Hepatocyte growth factor
HDL High-density lipoprotein
HMGB1 High mobility group box-1
HSC Hepatic stellate cell
IL-22 Interleukin-22
IR Insulin resistance
MASLD Metabolic dysfunction-associated steatotic liver disease
MASH Metabolic dysfunction-associated steatohepatitis
mRNA-LNP Messenger RNA–lipid nanoparticle
MSNs Mesoporous silica nanoparticles
NASH Non-alcoholic steatohepatitis
NAFLD Non-alcoholic fatty liver disease
NanoCys PEG–poly(cysteine) nanoparticles
NaYF4 Sodium yttrium fluoride
NM-FGF19 Non-mitogenic fibroblast growth factor 19
LCS-SeNPs Chitosan selenium nanoparticles
LDL Low-density lipoprotein
OA Oleic acid
PA Palmitic acid
PI3K/AKT Phosphoinositide-3-kinase/protein kinase B
PLGA Poly(lactide-co-glycolide)
PNM Platelet–neutrophil hybrid membrane
PNPLA3 I148M Patatin-like phospholipase domain-containing protein 3 (I148M variant)
PPARα Peroxisome proliferator-activated receptor-α
ROS Reactive oxygen species
siRNA Small interfering RNA
SCAR Steatohepatitis-associated circRNA ATP5B Regulator
SGLT2 Sodium–glucose cotransporter 2
STZ Streptozotocin
TEF Naringin treatment in tissue-engineered fatty
TG Triglycerides
TNF-α Tumor necrosis factor-alpha
TiO2 Titanium dioxide