Table 3.
Logistic regression analysis of preoperative risk factors associated with pathological upstaging in patients with cTa and cT1 bladder cancer based on complete case dataset.
| Variable | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age (per 10 year increase) | 1.24 (0.94–1.64) | 0.1 | ||
| Sex, male vs. female | 0.79 (0.41–1.53) | 0.5 | ||
| ECOG-PS, >=2 vs. 0–1 | 2.52 (0.71–8.92) | 0.2 | ||
| Smoking history | 0.70 (0.40–1.22) | 0.2 | ||
| History of NMIBC | 1.07 (0.66–1.73) | 0.8 | ||
| History of BCG | 0.79 (0.47–1.34) | 0.4 | ||
| Tumour multiplicity, multiple vs. solitary | 1.15 (0.67–2.00) | 0.6 | ||
| Size of tumours, >=3 cm vs. <3 cm | 1.86 (1.09–3.16) | 0.022 | 1.90 (1.06–3.40) | 0.031 |
| Clinical T stage, cT1 vs. cTa | 0.94 (0.69–1.30) | 0.7 | 0.86 (0.59–1.25) | 0.4 |
| Concomitant CIS (TUR) | 0.69 (0.41–1.17) | 0.2 | 0.74 (0.41–1.36) | 0.3 |
| Histological subtype (TUR) | 0.38 (0.15–0.92) | 0.033 | 0.40 (0.16–1.01) | 0.053 |
| NAC, >=2 cylcles vs. 0–1 cycle | 0.95 (0.50–1.81) | 0.9 | 0.65 (0.31–1.37) | 0.3 |
Significant values are in bold.