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. 2026 May 22;5(2):39. doi: 10.3390/muscles5020039
5′UTR 5′ untranslated region
AARE Amino acid response element
AIF Apoptosis-inducing factor
AMPK AMP-activated protein kinase
ATF4 Activating transcription factor 4
ATF5 Activating transcription factor 5
ATFS-1 Activating transcription factor associated with stress-1
BAK Bcl-2 Homologous Antagonist/Killer
BAX Bcl-2-associated protein X
BID BH3-interacting-domain death agonist
BIM Bcl-2 interacting mediator of cell death
c-Jun Cellular jun
C/EBP CCAAT-enhancer binding protein α/β/γ/δ
cAMP cyclic AMP
CARE C/EBP-ATF response element
CCA Chronic contractile activity
ChIP-seq Chromatin immunoprecipitation and sequencing
CHOP C/EBP homologous protein
ClpP Caseinolytic mitochondrial matrix peptidase proteolytic subunit
Cpn10 10 kDa chaperonin, mitochondrial
CRE cAMP response element
CREB cAMP response element-binding protein
CReP Constitutive repressor of eIF2α cphosphorylation
DELE1 DAP3-binding cell death enhancer 1
DISC Death-inducing signaling complex
DR4 Transmembrane death receptor 4
DR5 Transmembrane death receptor 5
DRP1 Dynamin-related protein 1
dsRNA Double-stressed RNA
eIF2B Eukaryotic translation initiation factor 2B subunit alpha
eIF2α Eukaryotic translation-initiation factor-2 alpha
EndoG Endonuclease G
ER Endoplasmic reticulum
ERα Estrogen receptor alpha
ETC Electron transport chain
fCLIP-seq Formaldehyde-mediated crosslinking and immunoprecipitation sequencing
FGF21 Fibroblast growth factor 21
FOXO3A Forkhead box 3A
GADD34 Growth arrest and DNA damage-inducible protein 34
Gadd45α Growth arrest and DNA damage-inducible protein 45 alpha
GCN2 General control nonderepressible 2 (serine/threonine protein kinase)
GDF15 Growth differentiation factor 15
GDP Guanine diphosphate
GEF Guanine exchange factor
GTTP Gamitrinib-triphenylphosphonium
HRI Heme-regulated inhibitor
HSP10 10 kDa heat shock protein
HSP60 60 kDa heat shock protein
HtrA2 High temperature requirement A2
HuR Human antigen R
IMS Intermembrane space
ISR Integrated stress response
ISRIB Integrated stress response inhibitor
JNK c-jun N-terminal kinase
LONP1 Lon peptidase 1
MAP3K4 MAP kinase kinase MEKK4
MAPK Mitogen-activated protein kinase
MEF Mouse embryonic fibroblasts
MEKK4 Mitogen-activated protein kinase kinase kinase 4
Met-tRNAi Methionyl-initiator tRNA
MFN2 Mitofusin 2
MKK3 Mitogen-activated protein kinase kinase 3
MKK4 Mitogen-activated protein kinase kinase 4
MKK6 Mitogen-activated protein kinase kinase 6
MOM Mitochondrial outer membrane
MOMP Mitochondrial outer membrane pore permeabilization
MQC Mitochondrial quality control
mtDNA Mitochondrial DNA
mtHSP60 60 kDa mitochondrial heat shock protein
mtHSP70 75 kDa mitochondrial heat shock protein
mTORC1 Mammalian/mechanistic target of rapamycin complex 1
mtRNA Mitochondrial RNA
MURE UPRmt response element
NADH Nicotinamide adenine dinucleotide (reduced)
NRF-1/2 Nuclear respiratory factor-1 and -2
NuGEMPs Nuclear genes encoding mitochondrial proteins
OAA Oxaloacetate
OMA1 Optic atrophy 1
OXPHOS Oxidative phosphorylation
p21 Cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1
PERK Protein kinase R-like ER kinase
PIC Preinitiation complex
PKR Protein kinase RNA-activated
PNPase Polynucleotide phosphorylase
PP1 Protein phosphatase 1
PP1c Protein phosphatase 1 catalytic subunit
PUMA p53 upregulated modulator of apoptosis
REDD1 Regulated in development and DNA damage responses 1
REs Response elements
ROS Reactive oxygen species
SIRT3 Sirtuin 3
Smox Spermine oxidase
SOD2 Superoxidase 2
TOM Translocase of the outer membrane
TRAIL TNF-related apoptosis-inducing ligand
uORF Upstream open reading frame
UPRmt Mitochondrial unfolded protein response
YME1L1 YME1-like 1 ATPase